Anti-CD6 Mouse Monoclonal Antibody (CF488A) [clone: C6/372]

Supplier: Biotium

BNC880372-100 BNC880372-500

75917-154EA 325.12 CAD

75917-154 75917-156

Anti-CD6 Mouse Monoclonal Antibody (CF488A) [clone: C6/372]

Antibodies

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellularscavenger receptor cysteine-rich(SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: CD6
Clonality: Monoclonal
Clone: Clone C6/372
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human

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