Anti-CD6 Mouse Monoclonal Antibody (CF405S) [clone: C6/372]

Supplier: Biotium

BNC040372-100 BNC040372-500

75917-150EA 325.12 CAD

75917-150 75917-152

Anti-CD6 Mouse Monoclonal Antibody (CF405S) [clone: C6/372]

Antibodies

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellularscavenger receptor cysteine-rich(SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CD6
Clonality: Monoclonal
Clone: Clone C6/372
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human

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