Anti-CD4 Mouse Monoclonal Antibody (CF647) [clone: EDU-2]

Supplier: Biotium

BNC470345-100 BNC470345-500

75895-654EA 325.12 CAD

75895-654 75895-656

Anti-CD4 Mouse Monoclonal Antibody (CF647) [clone: EDU-2]

Antibodies

This antibody recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: Clone EDU-2
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Chimpanzee, Human, Macaca artctoids, Orangutan

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