Anti-CD4 Mouse Monoclonal Antibody (CF640R) [clone: EDU-2]

Supplier: Biotium

BNC400345-100 BNC400345-500

75895-650EA 325.12 CAD

75895-650 75895-652

Anti-CD4 Mouse Monoclonal Antibody (CF640R) [clone: EDU-2]

Antibodies

This antibody recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.This MAb was characterized as human CD4 antibody at II and IV International Workshop on Human Leukocyte Differentiation Antigens.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: Clone EDU-2
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Chimpanzee, Human, Macaca artctoids, Orangutan

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