Anti-CD8A Mouse Monoclonal Antibody [clone: RIV11]

Supplier: Biotium

BNUB0333-100 BNUB0333-500

75910-748EA 380.65 CAD

75910-748 75910-750

Anti-CD8A Mouse Monoclonal Antibody [clone: RIV11]

Antibodies

This antibody recognizes a protein of 32 kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor, Leu2, and T8). CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8 T-cells expresses CD8 as heterodimer. Some subpopulation of CD8 T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain). The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase.

Type: Primary
Antigen: CD8A
Clonality: Monoclonal
Clone: Clone RIV11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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