Anti-CD3E Mouse Monoclonal Antibody (CF405S) [clone: RIV9]

Supplier: Biotium

BNC040322-100 BNC040322-500

75895-274EA 325.12 CAD

75895-274 75895-276

Anti-CD3E Mouse Monoclonal Antibody (CF405S) [clone: RIV9]

Antibodies

This antibody reacts with five invariable CD3 chains designated CD3y, CD3d, CD3e, CD3f, and CD3n with molecular weight ranging from 16-28 kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly intracytoplasmic. This MAb is particularly useful for induction of T cell activation in vitro and in vivo due to its unusual IgG3 isotype.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CD3E
Clonality: Monoclonal
Clone: Clone RIV9
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG3, kappa
Reactivity: Human, Mouse, Rat

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