Anti-CD36 Mouse Monoclonal Antibody (Biotin) [clone: 1E8.]

Supplier: Biotium

BNCB0314-100 BNCB0314-500

75894-990EA 325.12 CAD

75894-990 75894-992

Anti-CD36 Mouse Monoclonal Antibody (Biotin) [clone: 1E8.]

Antibodies

This antibody recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.

Type: Primary
Antigen: CD36
Clonality: Monoclonal
Clone: Clone 1E8.
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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