Anti-ITGAL Mouse Monoclonal Antibody (CF488A) [clone: DF1524]

Supplier: Biotium

BNC880312-100 BNC880312-500

75886-674EA 325.12 CAD

75886-674 75886-676

Anti-ITGAL Mouse Monoclonal Antibody (CF488A) [clone: DF1524]

Antibodies

This antibody recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: ITGAL
Clonality: Monoclonal
Clone: Clone DF1524
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human

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