Anti-Lewis A Mouse Monoclonal Antibody (Biotin) [clone: 7LE]

Supplier: Biotium

BNCB0311-100 BNCB0311-500

75955-844EA 325.12 CAD

75955-844 75956-814

Anti-Lewis A Mouse Monoclonal Antibody (Biotin) [clone: 7LE]

Antibodies

This antibody recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Type: Primary
Antigen: Not Applicable
Clonality: Monoclonal
Clone: Clone 7LE
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human, Mouse

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