Anti-MYB Mouse Monoclonal Antibody (CF640R) [clone: MYB286]

Supplier: Biotium

BNC400286-100 BNC400286-500

75920-990EA 325.12 CAD

75920-990 75920-992

Anti-MYB Mouse Monoclonal Antibody (CF640R) [clone: MYB286]

Antibodies

The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: MYB
Clonality: Monoclonal
Clone: Clone MYB286
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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