Anti-INS Mouse Monoclonal Antibody (CF647) [clone: E2-E3]

Supplier: Biotium

BNC470281-100 BNC470281-500

75954-836EA 325.12 CAD

75954-836 75954-838

Anti-INS Mouse Monoclonal Antibody (CF647) [clone: E2-E3]

Antibodies

This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: INS
Clonality: Monoclonal
Clone: Clone E2-E3
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Cow, Human, Mouse, Pig, Rabbit

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