Anti-IGKC Mouse Monoclonal Antibody (CF640R) [clone: KLC264]

Supplier: Biotium

BNC400264-100 BNC400264-500

75955-292EA 325.12 CAD

75955-292 75955-598

Anti-IGKC Mouse Monoclonal Antibody (CF640R) [clone: KLC264]

Antibodies

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Type: Primary
Antigen: IGKC
Clonality: Monoclonal
Clone: Clone KLC264
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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