Anti-KRT76 Mouse Monoclonal Antibody (Biotin) [clone: AE-3]

Supplier: Biotium

BNCB0257-100 BNCB0257-500

75910-486EA 325.12 CAD

75910-486 75910-488

Anti-KRT76 Mouse Monoclonal Antibody (Biotin) [clone: AE-3]

Antibodies

This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1); 64 kDa (CK3); 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Type: Primary
Antigen: KRT76
Clonality: Monoclonal
Clone: Clone AE-3
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Chicken, Cow, Dog, Human, Monkey, Mouse, Rabbit, Rat

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