Anti-Testosterone Mouse Monoclonal Antibody (Biotin) [clone: 4E1G2]

Supplier: Biotium

BNCB0250-100 BNCB0250-500

75976-012EA 325.12 CAD

75976-012 75976-014

Anti-Testosterone Mouse Monoclonal Antibody (Biotin) [clone: 4E1G2]

Antibodies

This MAb is highly specific to testosterone. Its affinity constant for testosterone is ~10¹⁰ M^-1. In competitive binding immunoassay, it reacts with testosterone 100%, 11-beta-hydroxy testosterone 3.3%, 17-alpha-methyl testosterone <0.1%, 5-alpha DHT 0.8%, estradiol <0.1% and progesterone <0.1%. Testosterone, a steroid hormone from the androgen group, is derived from cholesterol. Testosterone is primarily secreted in the testes, but the ovaries and adrenal glands also produce smaller amounts. It is the principal male sex hormone and is responsible for the maturation of sex organs and the development of male secondary sex characteristics. The hormone is also involved in the growth of muscle mass and increases bone density and maturation. It functions by activating the androgen receptor and converting to estradiol and activation of estrogen receptors. Testosterone has been employed therapeutically to treat many conditions including infertility, lack of libido, osteoporosis, height growth and bone marrow stimulation. Anti-testosterone antibody may also prove useful in identification of testicular tumors arising from interstitial cells.

Type: Primary
Antigen: Not Applicable
Clonality: Monoclonal
Clone: Clone 4E1G2
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: All species

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