Anti-ALPP Mouse Monoclonal Antibody (CF647) [clone: ALPP/238]

Supplier: Biotium

BNC470238-100 BNC470238-500

75970-380EA 325.12 CAD

75970-380 75970-382

Anti-ALPP Mouse Monoclonal Antibody (CF647) [clone: ALPP/238]

Antibodies

PLAP is a tissue specific, trophoblast-derived, 70 kDa, glycosyl-phosphatidylinositol (GPI)-anchored, dimeric, Zn2 metallo glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans, PLAP, germ cell AP (GCAP) and intestinal AP, are 90-98% homologous. Non-tissue specific AP is found in kidney, liver and bone. This MAb binds equally well to all common allelic variants (S, F, FS and I) of PLAP as to AP from normal human testis. This MAb can be used both as coating as well as tracer antibody in the same ELISA to detect PLAP in serum of S, F, FS and I phenotypes.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: ALPP
Clonality: Monoclonal
Clone: Clone ALPP/238
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human

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