Anti-MYOG Mouse Monoclonal Antibody (Biotin) [clone: MGN185]

Supplier: Biotium

BNCB0185-100 BNCB0185-500

75964-976EA 325.12 CAD

75964-976 75964-978

Anti-MYOG Mouse Monoclonal Antibody (Biotin) [clone: MGN185]

Antibodies

Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.

Type: Primary
Antigen: MYOG
Clonality: Monoclonal
Clone: Clone MGN185
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Cat, Human, Mouse, Pig, Rat

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