Anti-Granulocyte Marker Mouse Monoclonal Antibody (Biotin) [clone: BM-1]

Supplier: Biotium

BNCB0061-100 BNCB0061-500

75949-182EA 325.12 CAD

75949-182 75949-184

Anti-Granulocyte Marker Mouse Monoclonal Antibody (Biotin) [clone: BM-1]

Antibodies

This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells.

Type: Primary
Antigen: Granulocyte Marker
Clonality: Monoclonal
Clone: Clone BM-1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human

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