Human Recombinant BD-3 (from E. coli)

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC

100-192-5UG 100-192-20UG 100-192-100UG 100-192-500UG 100-192-1MG
75845-264EA 133.4 CAD
75845-264 75845-266 75845-268 75845-270 75845-272
Human Recombinant BD-3 (from E. coli)
Proteins and Peptides

Beta-Defensin 3 (BD-3), also known as DEFB-3, is a member of the defensin class of antimicrobial peptides. Beta defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. BD-3 expression is stimulated by interferon-gamma and is an important molecule during adaptive immunity. BD-3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria. Further, BD-3 blocks human immunodeficiency virus type 1 (HIV-1) replication through the downregulation of the HIV-1 co-receptor, CXCR4.


  • High quality
  • Low endotoxin
  • Affordable


Caution: For research use only.

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SPECIFICATIONS

Protein/peptide name BD-3
Protein synonyms DEFB-3
Environmentally Preferable
Protein/peptide type Recombinant
Protein Function Cytokine
Species Human
Source E. coli
Conjugation Unconjugated
Gene ID P81534
Sequence GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
Protease-free N
Animal-free N
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤0.1
Biological activity Bioactivity: No biological activity data is available at this time
Purity ≥95%
Grade RUO
Formulation 0.1% Trifluoroacetic acid (TFA)
Molecular weight 5.2 kDa
Reconstitution instructions Sterile 10 mM acetic acid at 0.1 mg/ml
Storage conditions –20 °C
Shipping temperature RT

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