Human Recombinant FNDC5 (from HEK293 cells)

Supplier: ADIPOGEN CORP MS

AG-40B-0153-C010 AG-40B-0153-3010
102980-330EA 458.46 CAD
102980-330 102980-332
Human Recombinant FNDC5 (from HEK293 cells)
Proteins and Peptides

Irisin is a recently described exercise and PGC1-alpha-induced myokine secreted by skeletal muscle in mice and humans. Irisin has been shown to induce browning of white adipose tissue, but this role has been questioned and a new function in the control of mass and strength of cortical bone has been reported. The membrane fibronectin type III domain containing protein 5 (FNDC5) can be cleaved by an unknown protease to release the Irisin protein (aa 32-143 for human) and potentially also the FNDC5 (extracellular domain, aa 32-153 for human).

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