Thermostable FEN1
Supplier: New England Biolabs (NEB)
M0645S
M0645S
103218-938EA
139.04
CAD
103218-938
CA103218-938
Thermostable FEN1
Enzymes
Thermostable Flap Endonuclease 1, FEN1, catalyzes the cleavage of 5' DNA flaps from branched double stranded DNA substrates, creating a 5' phosphate terminus
- Thermostable DNA and RNA endonuclease
- Catalyzes the cleavage of 5' DNA and RNA flaps from branched double stranded DNA substrates
- FEN 1 products can be ligated by DNA ligase to create double stranded DNA
- Heat inactivation not possible
FEN1 products can be ligated by DNA ligase to create double stranded DNA. In vivo, FEN1 is an essential component of the Okazaki fragment maturation pathway, and also plays a role in base excision repair.
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