Pierce™ Recombinant Protein L (from E. coli)

Supplier: Thermo Scientific

Pierce™ Recombinant Protein L (from <i>E. coli</i>)

Pierce™ Recombinant Protein L (from <i>E. coli</i>)

Pierce™ Recombinant Protein L (from <i>E. coli</i>)

Pierce™ Recombinant Protein L (from <i>E. coli</i>)

21189 77679 77680

CAPI21189EA 262.9 CAD

CAPI21189 CAPI77679 CAPI77680

Pierce™ Recombinant Protein L (from E. coli)

Proteins and Peptides

Purified (unconjugated) Thermo Scientific Pierce Recombinant Protein L is useful as the basis for preparing various kinds of probes or affinity media for detection or purification of mouse and human antibodies in immunoassays and antibody purification protocols.

Contains four immunoglobulin-binding domains per protein
Binds members of all classes of Ig (IgG, IgM, IgA, IgE and IgD) that contain kappa light chains
Binds single chain variable fragments (scFv) and Fab fragments that contain kappa light chains

Protein L is an immunoglobulin-binding protein that was originally derived from the bacteria Peptostreptococcus magnus, but is now produced recombinantly. Protein L has the unique ability to bind through kappa light chain interactions without interfering with an antibody's antigen-binding site. This gives Protein L the ability to bind a wider range of Ig classes and subclasses than other antibody-binding proteins. Protein L will bind to all classes of Ig (IgG, IgM, IgA, IgE and IgD). Protein L will also bind single chain variable fragments (scFv) and Fab fragments. Protein L binds kappa I, III, and IV in human and kappa I on mouse.

Form: salt-free powder
A280 of 0.1% solution: 0.80

Isoelectric point (pI): 4.8

Caution: For Research Use Only. Not for use in diagnostic procedures.

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