Sodium chloride 99.5-100.5% (by argentometric analysis, on dry substance), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient low in endotoxins, SAFC®

Supplier: EMD MILLIPORE – PCS CA EXCEP

Synonyms: HaliteSea saltNaClSaline

1.16224.9500 1.16224.5000 1.16224.9029 1.16224.9029 1.16224.9053 1.16224.9500 1.16224.9053
CA1.16224.9029EA 795.83 CAD
CA1.16224.9029 EM1.16224.9053 CA1.16224.9053 EM1.16224.9500 EM1.16224.5000 EM1.16224.9029 CA1.16224.9500
Sodium chloride 99.5-100.5% (by argentometric analysis, on dry substance), EMPROVE® EXPERT Ph. Eur., BP, JP, USP suitable for use as excipient low in endotoxins, SAFC®
Sodium chloride

Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).


Certifications: Corresponds to Ph. Eur., BP, JP, USP

Formula: NaCl
MW: 58.44 g/mol
Boiling Pt: 1461 °C (1013 hPa)
Melting Pt: 801 °C
Density: 2.17 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00003477
CAS Number: 7647-14-5

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Specification Test Results

Assay (argentometric; calculated on dried substance) 99.5 - 100.5 %
Identity passes test
Appearance of solution passes test
Acidity or alkalinity passes test
Bromide (Br) ≤ 0.005 %
Ferrocyanides passes test
Iodide (I) passes test
Nitrite (NO₂) (UV-absorption 354nm; 1cm; 10%; water) ≤ 0.01
Phosphate (PO₄) ≤ 0.0025 %
Sulfate (SO₄) ≤ 0.0200 %
Heavy metals (as Pb) ≤ 0.0003 %
Al (Aluminium) ≤ 0.00002 %
As (Arsenic) ≤ 0.0001 %
Ba (Barium) passes test
Ca (Calcium) ≤ 0.002 %
Fe (Iron) ≤ 0.0002 %
K (Potassium) ≤ 0.01 %
Magnesium and alkaline-earth metals (as Ca) ≤ 0.0100 %
Residual solvents (ICH Q3C) excluded by production process
Loss on drying (105 °C, 2 h) ≤ 0.5 %
Endotoxins (kinetic turbidimetric test) ≤ 2.5 I.U./g

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