Anti-PTCH1 Goat Polyclonal Antibody

Supplier: Pierce Biotechnology

PA5-18544

CAPIPA5-18544EA 3268.55 CAD

CAPIPA5-18544

Anti-PTCH1 Goat Polyclonal Antibody

Antibodies

This antibody is predicted to react with bovine, canine and porcine based on sequence homology. This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.

Recommended Dilutions: Western Blot: 1-3 ug/ml, Immunofluorescence: Assay-dependent, Immunocytochemistry: Assay-dependent

Type: Primary
Antigen: PTCH1 (patched 1)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Goat
Isotype: none
Reactivity: Human

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