Anti-KLF4 Goat Polyclonal Antibody

Supplier: Pierce Biotechnology

PA5-18058

CAPIPA5-18058EA 3269.49 CAD

CAPIPA5-18058

Anti-KLF4 Goat Polyclonal Antibody

Antibodies

This antibody is predicted to react with bovine, mouse and rat based on sequence homology. KLF4 (Kruppel-like factor 4 (gut)) is a transcription factor that can act both as an activator and as a repressor. KLF4 binds to the 5'-CACCC-3' core sequence, and binds to the promoter region of its own gene and it can activate its own transcription. It regulates the expression of key transcription factors during embryonic development. KLF4 plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. It is also involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Diseases associated with KLF4 include skin sequamous cell carcinoma and familial adenomatous polyposis.

Recommended Dilutions: Western Blot: 0.1-0.3 ug/ml

Type: Primary
Antigen: KLF4 (Kruppel-like factor 4 (gut))
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Goat
Isotype: none
Reactivity: Human

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