Anti-ABL1 Rabbit Polyclonal Antibody

Supplier: Pierce Biotechnology

PA512910

CAPIPA5-12910EA 3258.01 CAD

CAPIPA5-12910

Anti-ABL1 Rabbit Polyclonal Antibody

Antibodies

This antibody is predicted to react with mouse based on sequence homology. ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.

Recommended Dilutions: Immunofluorescence: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Dot blot: 1:500

Type: Primary
Antigen: ABL1 (c-abl oncogene 1, non-receptor tyrosine kinase)
Clonality: polyclonal
Clone:
Conjugation: unconjugated
Epitope:
Host: Rabbit
Isotype: none
Reactivity: Human

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