Human Recombinant NNT-1/BCSF-3 (from E. coli)

Supplier: Peprotech

450-18-2UG 450-18-10UG 450-18-100UG 450-18-250UG 450-18-500UG 450-18-1MG

10781-320EA 209.84 CAD

10781-320 10781-322 10781-324 10781-326 10781-328 10781-330

Human Recombinant NNT-1/BCSF-3 (from E. coli)

Proteins and Peptides

NNT-1/BCSF-3 is a neurotrophic factor with B-cell-stimulating capabilities. Expressed in the lymph nodes and spleen, NNT-1/BCSF-3 activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member β (LIFR-β) by binding and inducing the tyrosine phosphorylation of, these receptors. In vitro , it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss, and B-cell hyperplasia associated with increases in serum IgG and IgM. Recombinant Human NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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