Mouse Recombinant PDGF-BB (from E. coli)

Supplier: Peprotech

315-18-2UG 315-18-10UG 315-18-50UG 315-18-100UG 315-18-250UG 315-18-500UG 315-18-1MG
10780-768EA 223.76 CAD
10780-768 10780-770 10780-772 10780-774 10780-776 10780-778 10780-780
Mouse Recombinant PDGF-BB (from E. coli)
Proteins and Peptides

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two β chains (218 total amino acids).


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Order Now

SPECIFICATIONS

Protein/peptide name PDGF-BB
Environmentally Preferable
Protein synonyms Platelet-Derived Growth Factor-BB|Glioma-Derived Growth Factor (GDGF)|Osteosarcoma-Derived Growth Factor (ODGF)
Protein/peptide type Recombinant
Protein Function Cytokines and Growth Factors
Species Mouse
Source E. coli
Conjugation Unconjugated
Gene ID 18591 P31240
Sequence SLGSLAAAEP AVIAECKTRT EVFQISRNLI DRTNANFLVW PPCVEVQRCS GCCNNRNVQC RASQVQMRPV QVRKIEIVRK KPIFKKATVT LEDHLACKCE TIVTPRPVT
Protease-free Y
Endotoxin level Low
Endotoxin content >0.1 ng/μg
Biological activity Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity 0.98
Form Lyophilized
Formulation Formulation can vary. Please refer to product CoA for information.
Molecular weight 24.4 kDa
Reconstitution instructions Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions Store at –20 °C prior to reconstitution.
Shipping temperature Ambient

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR