Mouse Recombinant MIP-1beta (from E. coli)

Supplier: Peprotech

250-32-2UG 250-32-10UG 250-32-50UG 250-32-100UG 250-32-250UG 250-32-500UG 250-32-1MG
10780-350EA 233 CAD
10780-350 10780-352 10780-354 10780-356 10780-358 10780-360 10780-362
Mouse Recombinant MIP-1beta (from E. coli)
Proteins and Peptides

Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens, by regulating the trafficking, and activation state, of selected subgroups of inflammatory cells (.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Murine MIP-1β (CCL4) is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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