Human Recombinant IL-34 (from HEK293 Cells)

Supplier: Peprotech

200-34-2UG 200-34-10UG 200-34-100UG 200-34-250UG 200-34-500UG 200-34-1MG

10779-854EA 221.03 CAD

10779-854 10779-856 10779-858 10779-860 10779-862 10779-864

Human Recombinant IL-34 (from HEK293 Cells)

Proteins and Peptides

IL-34 is a homodimeric cytokine that is expressed in a range of tissues that include spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1, stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. Recombinant Human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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