Human Recombinant VCAM-1 (from HEK293 Cells)

Supplier: Peprotech

150-04-10UG 150-04-50UG 150-04-100UG 150-04-250UG 150-04-500UG 150-04-1MG

10779-476EA 209.84 CAD

10779-476 10779-478 10779-480 10779-482 10779-484 10779-486

Human Recombinant VCAM-1 (from HEK293 Cells)

Proteins and Peptides

VCAM is a 110 kDa, cell surface integral membrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. The primary function of VCAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 may play a vital role in the development of several diseases, including atherosclerosis and rheumatoid arthritis. The human VCAM-1 gene codes for a 715 amino acid transmembrane glycoprotein containing a 19 amino acid cytoplasmic domain, a 22 amino acid transmembrane domain, and a 674 amino acid extracellular domain. Recombinant Human VCAM-1 is a 74.1 kDa glycoprotein comprising the extracellular domain (674 amino acid residues) of VCAM-1. Monomeric glycosylated VCAM-1 migrates at an apparent molecular weight of approximately 90.0 kDa by SDS-PAGE analysis under reducing conditions.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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