Mouse Recombinant Granzyme (from Baculovirus (Insect cells))

Supplier: PeproTech

140-03-250UG 140-03-1MG 140-03-100UG 140-03-500UG

10779-372EA 10965.75 CAD

10779-372 10779-370 10779-374 10779-368

Mouse Recombinant Granzyme (from Baculovirus (Insect cells))

Proteins and Peptides

Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell-mediated immune responses, and can activate apoptosis in target cells by both caspase-dependent and caspase-independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant Murine Granzyme B is a glycosylated 227 amino acid protein, comprising the mature active portion of the murine Granzyme B precursor. The apparent molecular weight is 28.9 kDa by mass spectrometry.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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