Human Recombinant TGF-beta3 (from E. coli)

Supplier: Peprotech

100-36E-2UG 100-36E-10UG 100-36E-50UG 100-36E-100UG 100-36E-250UG 100-36E-500UG 100-36E-1MG

10778-938EA 229.35 CAD

10778-938 10778-940 10778-942 10778-944 10778-946 10778-948 10778-950

Human Recombinant TGF-beta3 (from E. coli)

Proteins and Peptides

The three mammalian isoforms of TGF-β, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes, including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes, which are stored at the cell surface and in the extracellular matrix. The release of the biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. The physiological role of TGF-β3 is still unknown, but its expression pattern suggests a role in the regulation of certain development processes. Recombinant Human TGF-β3 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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