Human Recombinant IGF-BP1 (from E. coli)

Supplier: Peprotech

350-10-5UG 350-10-25UG 350-10-100UG 350-10-250UG 350-10-500UG 350-10-1MG

10774-476EA 221.03 CAD

10774-476 10774-478 10774-480 10774-482 10774-484 10774-486

Human Recombinant IGF-BP1 (from E. coli)

Proteins and Peptides

IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high-affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa, cysteine-rich, secreted protein expressed in the liver, deciduas, kidneys, and in amniotic fluid, where it is the most abundant IGF-BP. Levels of IGF-BP1 in serum are lowest after food consumption. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant Human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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