Mouse Recombinant Adiponectin (from Hi-5 Insect cells)

Supplier: Peprotech

315-26-5UG 315-26-25UG 315-26-50UG 315-26-100UG 315-26-250UG 315-26-500UG 315-26-1MG

10774-364EA 209.84 CAD

10774-364 10774-366 10774-368 10774-370 10774-372 10774-374 10774-376

Mouse Recombinant Adiponectin (from Hi-5 Insect cells)

Proteins and Peptides

Adiponectin is an adipose-derived secreted protein containing 236 amino acid residues. It is relatively abundant in humans and rodents, accounting for about 0.01% of total plasma protein. The circulating levels of adiponectin are decreased under conditions of obesity, insulin resistance, and type II diabetes. Disruption of adiponectin in mice causes insulin resistance and neointimal formation. Conversely, administration of recombinant adiponectin suppresses hepatic glucose production, and reverses insulin resistance associated with both lipoatrophy and obesity. The protective role of adiponectin is attributed to its anti-inflammatory properties (e.g. ability to suppress expression of TNF-α and class A scavenger receptor in macrophages). Recombinant Human Adiponectin is a multimeric glycoprotein containing amino acids Val-21 to Asn-247 of the adiponectin precursor protein fused to an N-terminal histidine tag. Monomeric glycosylated adiponectin migrates at an apparent molecular weight of approximately 35.0 kDa by SDS PAGE analysis under reducing conditions. The calculated molecular weight of Recombinant Murine Adiponectin is 25.8 kDa.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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