Human Recombinant Flt3-Ligand (from E. coli)

Supplier: Peprotech

300-19-2UG 300-19-10UG 300-19-50UG 300-19-100UG 300-19-250UG 300-19-500UG 300-19-1MG

10773-612EA 229.35 CAD

10773-612 10773-614 10773-616 10773-618 10773-620 10773-622 10773-624

Human Recombinant Flt3-Ligand (from E. coli)

Proteins and Peptides

Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. Recombinant Human Flt3-Ligand is a soluble 17.6 kDa protein consisting of 155 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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