Human Recombinant TPO (from E. coli)

Supplier: Peprotech

300-18-2UG 300-18-50UG 300-18-100UG 300-18-250UG 300-18-500UG 300-18-1MG

10773-598EA 223.76 CAD

10773-598 10773-602 10773-604 10773-606 10773-608 10773-610

Human Recombinant TPO (from E. coli)

Proteins and Peptides

TPO is a lineage-specific growth factor produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo . TPO signals through the c-mpl receptor, and acts as an important regulator of circulating platelets. Human and murine TPO exhibit cross-species reactivity. The human TPO gene encodes for a 353 amino acid glycoprotein, which contains a 21 amino acid signal sequence, a 15 amino acid erythropoietin-like domain, and a highly glycosylated 179 amino acid C-terminal domain. Recombinant Human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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