Human Recombinant Oncostatin (from E. coli)

Supplier: PeproTech

300-10-250UG 300-10-1MG 300-10-50UG 300-10-100UG 300-10-10UG 300-10-2UG 300-10-500UG

10773-528EA 12171.72 CAD

10773-528 10773-518 10773-526 10773-516 10773-524 10773-522 10773-520

Human Recombinant Oncostatin (from E. coli)

Proteins and Peptides

Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi’s sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptors in hepatoma cells. OSM shares several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant Human Oncostatin M is a 25.7 kDa protein, containing 227 amino acid residues (full length precursor).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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