Mouse Recombinant Neuropoietin (from E. coli)

Supplier: Peprotech

250-25B-5UG 250-25B-25UG

10773-342EA 209.84 CAD

10773-342 10773-344

Mouse Recombinant Neuropoietin (from E. coli)

Proteins and Peptides

Neuropoietin is a newly identified member of the IL-6 cytokine family. Members of this family, including IL-6, IL-11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex formed of a CNTF receptor-α component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons, and could increase the proliferation of neural precursor cells in the presence of EGF and FGF-2. Interestingly, the human neuropoietin gene has evolved toward a pseudogene, suggesting that alternative signaling via CNTF is an effective compensatory pathway. Recombinant Murine Neuropoietin is a 19.8 kDa protein containing 183 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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