Human Recombinant TIGAR-TAT (from E. coli)

Supplier: Peprotech

150-14T-5UG 150-14T-25UG 150-14T-100UG 150-14T-250UG 150-14T-500UG 150-14T-1MG

10772-846EA 209.84 CAD

10772-846 10772-848 10772-850 10772-852 10772-854 10772-856

Human Recombinant TIGAR-TAT (from E. coli)

Proteins and Peptides

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other intracellular proteins into primary, as well as transformed, cells. Recombinant Human TIGAR-TAT expressed in

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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