Human Recombinant SPARC/Osteonectin (from CHO Cells)

Supplier: Peprotech

120-36-10UG 120-36-50UG 120-36-100UG 120-36-250UG

10772-698EA 209.84 CAD

10772-698 10772-700 10772-702 10772-704

Human Recombinant SPARC/Osteonectin (from CHO Cells)

Proteins and Peptides

SPARC/Osteonectin is a secreted, evolutionarily-conserved, collagen-binding glycoprotein that is involved in a variety of cellular activities. It is highly expressed in tissues undergoing morphogenesis, remodeling and wound repair. SPARC/Osteonectin and its related peptides bind to numerous proteins of the extracellular matrix (ECM), affect ECM protein expression, influence cellular adhesion and migration, and modulate growth factor-induced cell proliferation and angiogenesis. SPARC/Osteonectin consists of three domains: an N-terminal acidic region that binds calcium ions with low affinity, a module containing two EF-hand motifs that bind calcium with high affinity, and a cysteine-rich follistatin-like domain. Recombinant Human SPARC/Osteonectin is a glycoprotein containing 286 amino acids that migrates at an apparent MW of 43.7 kDa by SDS-PAGE analysis due to the effect of glycosylation. The calculated molecular weight of Recombinant Human SPARC/Osteonectin is 32.7 kDa.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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