Human Recombinant SPARC/Osteonectin (from CHO Cells)

Supplier: Peprotech

120-36-10UG 120-36-50UG 120-36-100UG 120-36-250UG
10772-698EA 221.22 CAD
10772-698 10772-700 10772-702 10772-704
Human Recombinant SPARC/Osteonectin (from CHO Cells)
Proteins and Peptides

SPARC/Osteonectin is a secreted, evolutionarily-conserved, collagen-binding glycoprotein that is involved in a variety of cellular activities. It is highly expressed in tissues undergoing morphogenesis, remodeling and wound repair. SPARC/Osteonectin and its related peptides bind to numerous proteins of the extracellular matrix (ECM), affect ECM protein expression, influence cellular adhesion and migration, and modulate growth factor-induced cell proliferation and angiogenesis. SPARC/Osteonectin consists of three domains: an N-terminal acidic region that binds calcium ions with low affinity, a module containing two EF-hand motifs that bind calcium with high affinity, and a cysteine-rich follistatin-like domain. Recombinant Human SPARC/Osteonectin is a glycoprotein containing 286 amino acids that migrates at an apparent MW of 43.7 kDa by SDS-PAGE analysis due to the effect of glycosylation. The calculated molecular weight of Recombinant Human SPARC/Osteonectin is 32.7 kDa.


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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SPECIFICATIONS

Protein/peptide name SPARC/Osteonectin
Protein synonyms ON|Secreted Protein Acidic and Rich in Cysteine|BM-40
Environmentally Preferable
Protein/peptide type Recombinant
Protein Function Cytokines and Growth Factors
Species Human
Source CHO cells
Conjugation Unconjugated
Gene ID 6678 P09486
Sequence APQQEALPDE TEVVEETVAE VTEVSVGANP VQVEVGEFDD GAEETEEEVV AENPCQNHHC KHGKVCELDE NNTPMCVCQD PTSCPAPIGE FEKVCSNDNK TFDSSCHFFA TKCTLEGTKK GHKLHLDYIG PCKYIPPCLD SELTEFPLRM RDWLKNVLVT LYERDEDNNL LTEKQKLRVK KIHENEKRLE AGDHPVELLA RDFEKNYNMY IFPVHWQFGQ LDQHPIDGYL SHTELAPLRA PLIPMEHCTT RFFETCDLDN DKYIALDEWA GCFGIKQKDI DKDLVI
Protease-free Y
Endotoxin level Low
Endotoxin content >0.1 ng/μg
Biological activity Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity 0.97
Form Lyophilized
Formulation Formulation can vary. Please refer to product CoA for information.
Molecular weight 32.7 kDa
Reconstitution instructions Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions Store at –20 °C prior to reconstitution.
Shipping temperature Ambient

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