Human Recombinant sFRP-1 (from HeLa Cells)

Supplier: Peprotech

120-29-5UG 120-29-20UG 120-29-100UG 120-29-250UG 120-29-500UG 120-29-1MG

10772-658EA 227.33 CAD

10772-658 10772-660 10772-662 10772-664 10772-666 10772-668

Human Recombinant sFRP-1 (from HeLa Cells)

Proteins and Peptides

Secreted Frizzled Related Proteins (sFRPs) modulate WNT signaling by binding directly to WNT proteins in a manner that affects their receptor binding and signaling capabilities. sFRP-1 is a widely distributed protein that can bind directly to WNT1, WNT2, and possibly other WNT proteins, and generally exerts anti-proliferative effects consistent with activity as a WNT antagonist. It also inhibits apoptosis, and has been found to be down-regulated in many solid tumors, but up-regulated in uterine leiomyomas. Recombinant Human sFRP-1 is a glycosylated 283 amino acid protein containing a cysteine-rich Frizzled homologous domain. The calculated molecular weight of Recombinant Human sFRP-1 is 32.5 kDa.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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