Human Recombinant TGF-beta1 (from HEK293 Cells)

Supplier: Peprotech

100-21-2UG 100-21-10UG 100-21-50UG 100-21-100UG 100-21-250UG 100-21-500UG 100-21-1MG

10772-034EA 222.64 CAD

10772-034 10772-036 10772-038 10772-040 10772-042 10772-044 10772-046

Human Recombinant TGF-beta1 (from HEK293 Cells)

Proteins and Peptides

The three mammalian isoforms of TGF-β, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes, including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes, which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. TGF-β1 is the most abundant isoform secreted by almost every cell type. It was originally identified for its ability to induce phenotypic transformation of fibroblasts, and recently it has been implicated in the formation of skin tumors. Recombinant Human TGF-β1 derived from

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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