Human Recombinant VEGF-B (from E. coli)

Supplier: Peprotech

100-20B-5UG 100-20B-20UG 100-20B-100UG 100-20B-250UG 100-20B-500UG 100-20B-1MG

10771-998EA 227.33 CAD

10771-998 10772-000 10772-002 10772-004 10772-006 10772-008

Human Recombinant VEGF-B (from E. coli)

Proteins and Peptides

VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surface-associated, disulfide-linked homodimers, and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a cysteine knot-like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant Human VEGF-B is a 38.0 kDa, disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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