Human Recombinant Myostatin (from E. coli)

Supplier: Shenandoah Biotechnology

Recombinant human myostatin

Recombinant human myostatin

100-22-100UG 100-22-1MG 100-22-500UG 100-22-10UG 100-22-2UG

10789-128EA 311.05 CAD

10789-128 10822-304 10789-130 10789-132 10787-450

Human Recombinant Myostatin (from E. coli)

Proteins and Peptides

Myostatin (GDF-8), a conserved member of the TGF-beta superfamily, is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size. Myostatin binds one of the two activin type II receptors (ACTRIIA, ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.

Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

Ordering information: Ships at room temperature; Store at 20°C upon delivery.

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