Human Recombinant PDGF-BB (from E. coli)

Supplier: Shenandoah Biotechnology

Human Recombinant PDGF-BB (from <i>E. coli</i>)

Human Recombinant PDGF-BB (from <i>E. coli</i>)

Human Recombinant PDGF-BB (from <i>E. coli</i>)

Human Recombinant PDGF-BB (from <i>E. coli</i>)

100-18-500UG 100-18-100UG 100-18-1MG 100-18-10UG 100-18-2UG

10787-436EA 324.75 CAD

10787-436 10787-438 10788-982 10821-868 10787-440

Human Recombinant PDGF-BB (from E. coli)

Proteins and Peptides

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.

Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

Ordering information: Ships at room temperature; Store at 20°C upon delivery.

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