Human Recombinant IL-17A (from E. coli)

Supplier: FUJIFILM IRVINE SCIENTIFIC, INC

100-87-100UG 100-87-1MG 100-87-25UG 100-87-5UG
10787-770EA 884.72 CAD
10787-770 10787-772 10787-774 10787-776
Human Recombinant IL-17A (from E. coli)
Proteins and Peptides

Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion.


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In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.


Caution: For research use only.

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