MAbPac™ RP LC Columns

Supplier: Thermo Scientific

MAbPac RP, 2.1 and 3.0mm Analytical Columns

MAbPac RP 1 mm Analytical Columns

MAbPac RP, 2.1 and 3.0mm Analytical Columns

MAbPac RP 1 mm Analytical Columns

088644 088645 088646 088647 088648 088649 303270 303270 303269 303183 303184

10783-106EA 1998.71 CAD

10783-106 10783-108 10783-110 10783-112 10783-114 10783-116 75997-786 76320-034 76420-870 76420-874 76424-342 76424-344

MAbPac™ RP LC Columns

Chromatography Columns

MAbPac RP is a reverse phase (RP) column specifically designed for separation of intact monoclonal antibodies (mAbs) and mAb fragments.

Superior resolution power for monoclonal antibodies and related substances
Ideal for small precious samples
High efficiency with low carry-over
For direct injection into MS: 75 to 150 µl/min
Wide operating pH range
High temperature stability, up to 110 °C
Optimized for low flow rates

The stationary phase is fully compatible with mass spectrometry friendly organic solvent such as acetonitrile and isopropanol, as well as low pH eluents containing trifluoroacetic acid or formic acid.

The MAbPac RP is based on wide-pore 4 µm polymer particles that are stable at extreme pH (0 to 14) and high temperature (up to 110 °C). The wide- pore size of polymeric particles enables efficient separation of protein molecules with low carry-over.

This column can be used to separate intact mAb and variants, light chain (LC) and heavy chain (HC), Fc and Fab fragments, scFc and F(ab’)2 fragments , using LC/UV or LC/MS.

Ordering information: Guard cartridges require use of the corresponding guard holder. See Acclaim Guard Kit Holder and Coupler V-2.

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