Anti-CTLA4 Mouse Monoclonal Antibody [clone: BNI3]

Supplier: Tonbo Biosciences
40-1529-U100 40-1529-U500
10208-684EA 135.88 CAD
10208-684 10208-686
Anti-CTLA4 Mouse Monoclonal Antibody [clone: BNI3]
Antibodies
The BNI3 antibody is specific for human CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator ofMore Product Information
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