Anti-KRAS Rabbit Polyclonal Antibody

Supplier: Proteintech
12063-1-AP-150UL
10089-368EA 709.42 CAD
10089-368
Anti-KRAS Rabbit Polyclonal Antibody
Antibodies
KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon . KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation . KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms, a and b. This KRAS antibody (12063-1-AP) is a Pan-RAS antibody.

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200; IP: HeLa Cells, 1:500-1:5000; FC: HeLa Cells, N/A

Type: Primary
Antigen: KRAS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR