Anti-CD80 Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: 16-10A1]

Supplier: Tonbo Biosciences

C57Bl/6 splenocytes were unstimulated (left panel) or stimulated for 3 days with LPS (right panel) and stained with 0.125 ug PE Anti-Mouse CD80 (50-0801) (solid line) or 0.125 ug PE Armenian Hamster isotype control (dashed line).

C57Bl/6 splenocytes were unstimulated (left panel) or stimulated for 3 days with LPS (right panel) and stained with 0.125 ug PE Anti-Mouse CD80 (50-0801) (solid line) or 0.125 ug PE Armenian Hamster isotype control (dashed line).

50-0801-U025 50-0801-U100

10051-274EA 71.1 CAD

10051-274 10051-276

Anti-CD80 Armenian Hamster Monoclonal Antibody (PE (Phycoerythrin)) [clone: 16-10A1]

Antibodies

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Type: Primary
Antigen: CD80
Clonality: Monoclonal
Clone: 16-10A1
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity:

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